Boxcar? Carmax?? BoxCarmax!
The Liu Lab recently published a new DIA method named BoxCarmax, which is a high-selectivity data-independent acquisition mass spectrometry method for the analysis of protein turnover and complex samples! The method is highly multiplexing at both MS1 and MS2 levels. BoxCarmax incorporates the sensitivity improvement of BoxCar MS1 acquisition (Initially developed by Mann group) through four sample injections and the selectivity improvement of MS2 through non-consecutive ac