Dr. Yansheng Liu received the 2026 Yale Cancer Center Class of ’61 Cancer Research Award  in recognition of his laboratory’s contributions to quantitative proteomics and protein turnover research in cancer. This award highlights our ongoing efforts to develop advanced mass spectrometry–based approaches to understand how proteome dynamics shape cancer biology.

How aneuploid cells tolerate chromosome arm gains or losses remains an open question. Using an isogenic human lung cell model with either chromosome 3p loss or 3q gain, combined with quantitative mass spectrometry and isotopic labeling, we reveal distinct proteostasis mechanisms for gain- and loss-type aneuploidy. Surprisingly, while compensation for 3q gain is primarily driven by increased degradation of excess protein complex subunits, 3p loss is neither counteracted by glo

Please come to our oral and poster presentations and chat with us!!

We are thrilled to announce that our latest study, "Turnover Atlas of Proteome and Phosphoproteome Across Mouse Tissues and Brain...

As we know, the human plasma proteome is crucial for clinical applications! The Matthias Mann lab and colleagues just published a...

Since publishing his first paper in 2010, Dr. Liu's Google Scholar citations have surpassed 10,000 as of January 2025, with his most...

We just have a really nice retreat at Danford’s in Port Jefferson, NY!! Please see the group pictures below.

What is your current position and location? I am an Associate Professor in the Department of Pharmacology at Yale University School of...